Antimicrobial Non-leaching Nitrile Disposable Gloves

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The world's first non-leaching antimicrobial nitrile disposable gloves that kill up to 99.999% of microbes. 

A new type of medical examination glove with built-in antimicrobial technology to fight infection and combat antimicrobial resistance, providing active protection against Healthcare Associated Infections (HAIs). Activated by light and oxygen, and able to kill up to 99.999% of microbes, these Antimicrobial Gloves provide an extra active layer of protection to healthcare workers.

Antimicrobial Gloves actively reduce the risk of infection transmission from an infection source to a susceptible patient. The active ingredient on the glove is a photosensitiser which generates singlet oxygen when exposed to light. This singlet oxygen oxidises the bacteria’s protein and lipid, thus leading to the death of microbes and bacteria within just five minutes of contact. This technology, built into gloves, also removes the need for additional solutions and chemicals.

The antimicrobial nitrile gloves are non-leaching, meaning that the active ingredient will not transfer to people or surfaces. These gloves are also skin-safe, being non-irritating and non-sensitising, meaning you can wear them safe in the knowledge they are not damaging or irritating your skin.

Additional information

Glove Size

Small (pack 100), Medium (pack 100), Large (pack 100)

Do antimicrobial gloves replace the need for hand hygiene?
Although the glove has been found effective against a wide range or microbes, it does not replace the need for hand hygiene. AMG serves as an extra precaution or tool to help mitigate the spread of HAI. Protocols for hand rubbing or hand washing should still be performed before donning and after removing gloves.

What does non-leaching mean? Is it safe?
The antimicrobial gloves are designed to be non-leaching in order to ensure the active ingredient does not transfer to the patient. To further ensure the safety of the active ingredient, the gloves have been tested for biocompatibility. ISO 10993 biocompatibility testing conducted on the inside and external surface of the gloves have confirmed that the gloves are non-sensitizing, non-irritating, non-toxic (oral) and non-cytotoxic. The Modified Draize-95 test was also conducted where both the inner and outer surfaces of the gloves were tested on human skin. The gloves provided no clinical evidence of inducing allergic reactions. Finally, tested at Intertek UK, the gloves were extracted using water, artificial saliva, artificial sweat and alcohol at room and body temperature. No active could be found extracted from the gloves’ inner or outer surface.

How does singlet oxygen work?
In this technology a special dye is used. The dye absorbs visible light. The dye is thus raised from a ground state to an excited quantum state, in which an elevation in energy takes place. The energy then transfers to a proximal oxygen molecule found in the air, causing the oxygen molecule to also rise to an excited quantum state. The ground state of oxygen present in air, is a triplet electronic configuration. Upon sensitization by the dye molecule, the electronic configuration changes and enters the singlet state. This singlet oxygen state is reactive and more oxidative compared to ground state oxygen and therefore, is able to kill microbes such as bacteria by oxidizing the cells’ protein and lipid. Using the dye as a catalyst, singlet oxygen can be generated continuously as it absorbs light and air.

What are the advantages of using singlet oxygen antimicrobial systems?
Singlet oxygen is a non-selective system that can react rapidly against many microbial components. There is not one single protection mechanism that bacteria can protect itself from singlet oxygen. This is in contrast to antibiotics, which need very specific mechanisms to treat a patient. As singlet oxygen is transient, it does not lead to the release of persistent biocides into the environment. As such, Abena Antimicrobial Gloves transforms the standard
examination glove from a passive medical device to a medical device with active protection, which will actively reduce or inhibit microbial colonisation.

What is the amount of light needed to activate the Antimicrobial Gloves?
Testing of AMG glove has been conducted at general lighting conditions at hospitals of 1000 lux and 500 lux. Results show that there was no significant difference in bactericidal efficacy. Further testing at lower light levels are underway.

Would differences in lighting type affect the efficacy of Antimicrobial gloves (for example – LED, fluorescent, incandescent light bulb)?
No. The glove is activated by any white light source. It is specifically activated by light in the 600 – 700 nm region but all white light sources contain this, otherwise they would be coloured.

Will the dye be depleted if the Antimicrobial Gloves are continually exposed to light?
No. As long as there is light and oxygen, the gloves are active. Heat-aged gloves (accelerated aging equivalent to 3 years shelf life) did not show significant difference in bactericidal efficacy compared to fresh gloves. The gloves were also exposed to “light” (equivalent to 30 days in an open box environment). Again, there was no significant difference in bactericidal efficacy compared to fresh gloves.

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